Italian neurosurgeon Sergio Canavero just practised for his proposed human head transplant by transplanting a second head onto a rat. In multiple iterations. None lived for longer than 36 hours, but that’s a hell of a lot better than the results from 20th century animal head/brain transplants.
The isolated beating heart at the beginning of that video looks macabre, but those animal organ experiments directly led to human organ transplants, which are commonplace now.
Canavero’s full paper is here, but it’s not public access. And frankly, that sucks. All academic knowledge should be free to read and not held ransom by journals.
Canavero used a third rat as a blood bag to keep the blood pressure up in the donor rat and the recipient rat during surgery.

Maybe Canavero will attempt his human transplant this year as promised, maybe not. But someone will, somewhere, eventually.
Head transplants work on the basis that that bit of us that is “me” lives in our brains is a fixed unchanging essence, and our bodies are only interchangeable shells we use for ambulating and oxygen processing. But this ignores the fact we’re embodied beings: we experience reality through and in our bodies. For one thing, our bodies are home to at least as many bacterial cells as human cells. There’s increasing evidence that our bacteria alter the way we think, feel, and love: like the outgoingness of humans infected with toxoplasma gondii, or the link between gut bacteria and obesity.
Transplanting a brain onto another body isn’t just giving an existing personality a new home, it’s creating a whole different being. I think we should go for it, but we have to acknowledge we can’t know what the outcome going to be like.
The future is barreling toward us and we’re not ready.